I really hope Alex Wesker to be completely different than Albert. I'd like to see what happened to the research, and it'd be cool if Alex were a girl. I don't want Alex Wesker to be a copy of Albert Wesker.
Well if we are to go by what was said on the Resident Evil wiki site.
The text in Lost in Nightmares suffered from being translated to English.
Even though the English translation never mentions whether he is a boy or a girl the Japanese translation refers to him as a "He".
Not sure if it true since I have never seen the japanese version of the files in Lost in Nightmares.