I mean, who was nemesis (in the game) before he/she became nemesis. I really think he was wesker (if we only view things out up to RE 3). I mean by RE3 plot, wesker was dead. He was only revived by the time of RE:CVX. That means the plot now contains a big hole. If we use wesker report 1 as a basis, that he was revived by the wonder virus given by William Birkin, then why on earth Umbrella was still researching all this subordinate viruses. So, i think the revival of wesker sort of screwed nemesis's past.