I would go with either Leon or Wesker.
I disliked Leon in RE2, RE4, and Degeneration, but I loved the way he was written in Darkside Chronicles. In that game, he is a well developed, interesting character with a likable personality.
I liked Wesker in RE0, RE1 (both the original and REmake), and Code: Veronica/Code: Veronica X. Beyond that, he gets on my nerves. I hate how Capcom had him go from being a selfish, power-hungry character with a Machiavellian philosophy to a typical raving mad man who wants to re-create the world based on a eugenic principle with him as its ruler.
As for Chris, I have never liked him, since he is a boring character devoid of a personality.