If the guy voicing him in RE5(and UC for that matter) didn't sound so fake and rehearsed, then I might be able to say something positive about him, but it was really horrid.
Had RE5 been your first game, DC Douglas' impression for Wesker may have been acceptable, or even cool, but if you have been playing since before, the difference is very noticable. As Richard WAugh pretty much made the voice, what with CVX, RE0 & RE4 under his belt, in addition to the Wesker's Report.
Douglas however has a weaker voice, and it shows. He kind of sounds like Peter Jessop from the REmake, but he is definately trying to sound like Waugh, that is where he fails, I would prefer if he did his own thing all together, instead of butchering the voice.
Furthermore, the trenchcoat looks stupid, for his character, his entire outfit just seems, over the top and lame, although I will admit without the coat it looked okay. However, the coat went all the way down to his feet, with a slit all the way up to the lower back, so in action, the two flaps fly around in the wind, which just looks really stupid.
I have lost so much respect for his character recently, as his personality and voice and everything are just not him at all. Wesker isn't an athletic guy, nor is he a gymnast, so seeing him flying around doing backflips, barrel rolls, etc, in mid air(which really wasn't helping him dodge bullets at all, if anything it would probably allow him to get hit), just seemed really illogical and stupid.
I can deal with a crappy voice, if it were for the character being like he should, and I could deal with the change in character, had he sounded like he should...Capcom is just pulling out all the stops there...which ironically coincides with the departure of Shinji Mikami.