I actually kind of disagree about using Billy if you're going to play with them both together, TBH.
I found that when I used Billy instead of Rebecca that she would take hits far more often (especially with the mimicry Marcuses) than when I played her. I found that it was better to take control of Rebecca as my main character because I'm better at avoiding damage than the AI. Since she has less health it makes sense to play her in the way where she takes the least amount of damage.
But, if you're happy to play it with just one character Billy has more health even if he can't mix herbs so he's the logical choice.
In Leech mode I'd suggest only using Billy, just clear everything out with him and bring Becky in to mop up leeches after. You don't have to share guns and ammo that way, either.
I found that when I used Billy instead of Rebecca that she would take hits far more often (especially with the mimicry Marcuses) than when I played her. I found that it was better to take control of Rebecca as my main character because I'm better at avoiding damage than the AI. Since she has less health it makes sense to play her in the way where she takes the least amount of damage.
But, if you're happy to play it with just one character Billy has more health even if he can't mix herbs so he's the logical choice.
In Leech mode I'd suggest only using Billy, just clear everything out with him and bring Becky in to mop up leeches after. You don't have to share guns and ammo that way, either.
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