An e-mail shown from Capcom's viral marketing site "nohopeleft". If this e-mail says the truth, my thoughts:
1. Uncle planning IVY speech. IVY = Ivy University, the place where the president will make his speech. Obviously this "uncle" is the president, but they call him uncle. Sender was "cousin S", which was sent to someone named "mother".
The three may be related in some way (surely not blood relatives, of course, but in some other way). To what extent, I wouldn't know, but the hints of "family" should pretty much justify it.
Mother = possibly Carla Radames/Ada? Could this "mother" be the main antagonist?
No idea about cousin s though. A partner? An agent? HUNK? What does the "S" stand for? "Sherawat"? "Sherry"?
2. Reflects badly on the family. This means that the president may be planning on "exposing" something about the "family".
3. RC incident will be exposed. As said above...
4. "Unstable". This is an odd statement. This somewhat does provide further proof of the "relationship" between the president with this "cousin" and "mother", as being part of a single "family", as the president's plans of exposition is an "unstable" action, probably indicating that he was defecting from them.
5. Family action needed to avert crisis. Voila, the death of the president. They needed to "do" something to stop the president from possibly exposing or at least, ruining the reputation of this "family". Hence, the possibility of starting an epidemic within the city (or perhaps originating from the place where the president was) in order to avoid the "crisis".