When I say this, I mean characters who Wesker has a history with so Sheeva is out, so besides Chris, who would have stood the best chance against Wesker:
1. Jill
2. Barry
3. Rebecca
4. Krauser {if he lived}
5. Ada
When did Claire or Leon ever meet Wesker?
Oh yeah, i forgot about CV, if Claire got her ass kicked then, I doubt it would change now, and are we talking RE 2 leon or RE 4 leon?
LOL, I like Leon but he'd be lucky to knock wesker's sunglasses off him like Chris did
But u forgot that the majority of battles Leon is in, Ada always has to save him...
Sorry, what i meant was Leon always needed Ada, Chris managed to hurt wesker a bit in CV without anyone's help...
Ada would probably use both men for her own deeds, whatever they are...
He still had his powers in CV, the only time he was still human was re0 and remake
I kinda doubt Ada cares for Leon romantically, she probably needs him for her own goals