Take the Shotgun SA as a secondary weapon.
Take this path when you get to the Honeycomb maze:
Left Door
Right Door (where the Automatic Pistol Ammo is)
Left Door
The only door there
Right door (after defeating the Crimson Head)
The only door there (after defeating the BOWs)
Right door (camera will automatically face there)
Throw a grenade there.
Collect all the ammo until you either leave, or can't hold anymore. You'll then be able to leave and find your way to Talos
Take out whatever Automatic Pistol ammo you have to destroy the rest of the glass, and take the ammo.
With Talos, throw a grenade at him as soon as you can, then hide. Shoot him with your Automatic Pistol whenever you can. Do the dodge commands right. Also aim for that silver part of his rocket launcher. That'll temporarily break it.
After the first phase, Talos will mutate. Do the next dodge commands right. Aim at those red spots on his armor. If he uses his tentacles, hit the tentacles, then the stuff falling on you with your Shotgun or Handgun. After Talos comes crashing down, aim for that red globe thing with your Automatic Pistol. He'll eventually get up and try to grab you. When that happens, he'll also use his tentacles, shoot the tentacles first, then the face. He'll pass out again, revealling the globe thing. Shoot it. Repeat.