Possible.
But it seems that there's not a single soul in that house at all, well, except for Wesker and Spencer though. If Wesker has a soul.
It looks like as if Jill Valentine just used her "Master of Unlocking" prowess and infiltrated the mansion with ease, and not one guard or at least employee screaming "Intruders!" or some nice ol' butler to welcome them in Spencer's not-so-humble abode.
Or Wesker could've killed them all and threw their bodies out. Its really hard to decipher his eccentric and psychotic mind. =/