I don't think they should be admissible in court. Lie detectors depend on changes in the body's physiology that correspond to lying, ie racing pulse, sweating, etc. Thing is, if you're an overly nervous person like I tend to be, I would fail in no time because nervousness often manifests itself with similar physiological changes.
Things can be said about people that are the opposite of myself. For example. My husband has Asperger's Syndrome. He also has two degrees in Criminal Justice. Over the course of his studies, one of the things they did in class was give students lie detector tests. Due to his Asperger's, he doesn't feel emotions the way your average joe would, and he was easily able to fool the lie detector. The same thing happens with psychopaths. They don't feel empathy or guilt and so they tend to commonly fool lie detectors.
They are too unreliable for many reasons on both ends of the spectrum of potential subjects being tested. I think they would be better off trusting an MRI or relying on body language or both, as opposed to lie detectors.