So, I was reading the RE Wikia, which I know, isn't always reliable, however, it is right quite a bit...And I found this peice of information...Do with it what you will, but there is a chance we may see Billy again in future installments...Whether they are main game or spin-off who's to say...But take a look...
During The NYC 2011 Comic-con, a Capcom representative answered questions regarding his status and he responded: " Billy Coen is still in the Resident Evil universe; we do have plans but nothing concrete so we can't confirm or deny Billy Coen returning back to the franchise because anything is possible."[1]
During The NYC 2011 Comic-con, a Capcom representative answered questions regarding his status and he responded: " Billy Coen is still in the Resident Evil universe; we do have plans but nothing concrete so we can't confirm or deny Billy Coen returning back to the franchise because anything is possible."[1]