Resident Evil goes completely "Star Wars" on itself and Wesker reveals, during the final confrontation in CV, that he is Chris' and Claire's father.
At the end of the final RE game, we get a cutscene where Chris wakes up in a mental hospital next to Leon, Jill and Claire and it turns out the events of R.E were all just a product of their fantasy and they are all mentally ill and therefore have hallucinated everything combined with suppressed memories.
that would be the best fanfic ever.kinda reminds me of sucker punchAnd Wesker is their doctor.