Every long time fan wants the franchise to be handed back to Shinji Mikami, but that's not gonna happen cause of 2 reasons:
1: Capcom is run by a president named "Money"
2: Shinji Mikami himself is disgusted with what Resident Evil has become and has no interest in returning to the IP.
I haven't listened to the interview yet because I'm at work, but judging from some reactions here, Capcom really did not know what the hell they were doing lol.
I think Shinji would be interested if a reboot was in the question as opposed to continuing a story he feels Capcom ruined.
And Capcom would be willing to do it if they thought his involvement would bring big bucks (which it would IMO).