All kinds of YES for this game! I absolutely loved the first one, and the story was left wide open for sequels.
As people have been quick to point out, the TerraSave shirt suggests that Claire will most likely be the main protagonist. If you ask me, it's about time my favorite RE lady returns. The last time we saw her in canon was Degeneration, which seems like so long ago now.
Also, the infection bracelets seem like an interesting concept. I'm wondering if that has become a standard-issue civilian accessory at this point in time. In a world where bioterrorism is such a looming threat, you would think something like that would have been required by law sooner. I'm also wondering if it will tie into the gameplay somehow. Perhaps you can get infected and your bracelet will slowly fade from green to red unless you cure yourself with a blue herb or something. Anyway, that's just my speculation, I feel like I'm rambling in text now XD
Regardless, this trailer has me hyped, and I'm looking forward to getting more information