His voice is so iconic.
When I played RE2 the first time when I was like 11, I didn't know that the B scenario changed the game for you. So, I just played Leon A over and over again. Then, like a year later - a friend told me that I never finished the game because I never played the B scenario. Well, I was used to Leon, so I decided to save his playthrough for the B scenario since it was supposedly harder. And I am glad I did. His weapon cache is WAY better than Claires.
I will never forget how proud I was for beating that B scenario for the first time (especially since Mr. X killed me probably like 18 times before I did)... and then I saw the REAL ending and I heard Leon say, "It's up to us to take out Umbrella." And then one of my top 5 RE songs plays after it.
Paul's voice will be the iconic moment I remember about finally beating that game. RIP to a legend.