I can only speak for how I know it to work in this country and this country's education system but as far as focusing study on their topic of interest, choosing which universities to apply to, and all that long-term stuff... well, there is no parenting that. If your child doesn't have the drive to pursue a career at age 18, then they just don't. Some people don't figure that out until later. All you can do is encourage areas where they show promise, interest, or ideally, both.
Curfews? Ease up on them around age 16, I'd say. 11 pm is a good one. Just late enough to not be a hard ass, early enough to be reasonable. Have your "no sex, no drugs, no rock 'n roll" rules in place fully expecting them to be broken. If they're messing around when they're older, they'll still hear that voice going "I told you so." At age 18, immediately stop saying a thing. That worked for my parents. Realizing you've lost a safety net can make you think twice about how you act out. Maybe this doesn't apply to every kid, but it worked on me.
The kid is going to pursue sex when they discover it. Nothing is going to stop them except their own teenage awkwardness. They're going to try smoking or drugs depending on how bad of influences their friends are; measured against their own maturity. Realistically none of that can be stopped, but I think it's a good idea to enforce with an iron fist that it's a bad idea.
Call me a hypocrite. I don't care. I didn't start smoking pot until I was 17 and even then I should have waited longer. All of the "it's harmless" arguments for pot, alcohol, nicotine, whatever fall flat when you're talking about a pubescent brain. Those chemical reactions will alter how the brain develops with FAR more impact during those years. In extreme cases, it's immediately noticeable. Will it bring their life to ruin? Probably not but that doesn't mean there is no negative impact. As Chef once said "Look children: this is all I’m gonna say about drugs. Stay away from them. There’s a time and a place for everything and it’s called college (USA terminology, mind you)."