The battle ground for the Heisenberg fight is oblong shaped, sideways as you enter the area. That combined with the fact that the cannon sends him far away from you, means going to the far left or right at the start, and using the cannon only when he's almost within striking range, will make things easier. The only caveat is it's going to make seeing his weak spots a bit harder, but anyone attempting VoS has probably already beat him enough times to remember where they are.
If you may mean just the on-foot part of this fight though, after the vehicle is destroyed, there is a strategy for that too. I'm not sure if it works on VoS, but I don't see why it wouldn't. The trick is to immediately go right up against his front side once you gain control again on foot, and pummel him with the shotgun. This was actually a faster kill method for me than explosive rounds. The reason I feel it should work on VoS, is in this position he cannot hit you, as it's too close for his long mech arms to reach.
The only thing that would make this on-foot tactic possibly doubtful on VoS, is if he somehow is able to move much faster on that difficulty, and can get away from you.