I don't know if I've ever mentioned it here before, but I did once suggest the idea of revisiting the remnants of Raccoon City for a sort of series "ending" and seeing them do exactly that is pretty goddamn awesome.
Dusk Golem has been touting this game as an endpoint of the series, with Capcom wanting to move away from the status quo and numbered entries and tell stories with new characters but also potentially visit earlier points in the timeline with the classic protagonists. This is something he originally speculated back when the data leak happened that revealed the codename "Apocalypse" for RE9, which was rather fitting in hindsight.
Personally, I really like this idea and I think there might even be evidence to suggest this being the direction they've been taking with the series. The remakes for example seem to now serve a much bigger purpose than originally thought. Especially the order in which they've chosen to remake them. Resident Evil 2 and 3 got to re-establish the events of Raccoon City, which will now be revisited in RE9, which will no doubt carry over assets and locations from both games as we saw with the destroyed RPD, creating a surreal before and after effect after having experienced the remakes.
Dusk Golem has also claimed that the game is acting as a conclusion to the Leon "trilogy" which explains why they did RE4 before Code Veronica. How it ties into 9 is still up in the air, but Leon is said to still be the main protagonist of RE9 and is apparently visible in the trailer as well. Likely the pair of legs we see walking on the sidewalk in the rain. He still stands by Jill having been removed from the game, so it's likely Nicole Tompkins is voicing a new character as she did in Village. Given the concept of returning to Raccoon City, not having Jill seems like a huge f*cking missed opportunity.
It's honestly a little underwhelming to have a finale of sorts only star one of the classic protagonists. I would have even respected the decision to center the story around a new protagonist, so long as her story is intertwined in some way to a bigger plot involving each of the main protagonists. That way, you get to feel like the player, learning and uncovering the plot, while coming across familiar faces and past locations for the final time.
But if there really is some grand plan here to synergize remakes with new stories and possibly revisit earlier points in the timeline, then maybe this game is only really closing off one part of the series as there's still a very clear Chris shaped hole here. Based on the trailer and story direction, I can't imagine how this is meant to tie into Village's ending at all. This is where I think Capcom has been intentionally leaving gaps open to revisit later, because we are given a tease of Chris' next mission only for the Shadow's of Rose DLC to take the wind out of it and skip forward in time and tell us Chris is alive. If they're ever going to tell this story, perhaps they'll use remakes of the Chris-centric games to get us there like they're apparently doing for Leon here?
Resident Evil 4 remake also seemed to leave another story open with Krauser, who's entire backstory is completely changed as well as the events which we originally knew as Operation Javier. I think there was an article by IGN a while back where one of the devs kind of responded to a question regarding the change of Krauser's story and it seemed like it was an intentional choice but couldn't elaborate any further. There's even the strange post-credits scene in the RE3 remake which shows Jill grabbing the broken vial as if there was more to her story post-RE3.
Now with the massive Outbreak connection, which was first teased in RE7 and was then followed by remakes of 2 and 3, it seems very likely that they'd want to remake the Outbreak games so players can not only experience where these new characters come from, but also return to Raccoon City after seeing it in ruins. RE9 did supposedly start development as an open-world co-op game, so maybe it's possible that work was originally meant to pave the way for Outbreak games too.