i think it wud be some ****ty burnt out old building, that still has like a handful of workers, or probably just wesker, but since umbrella supposed to have been exposed and there stocks crashed, i dont think they wud be a massively state of the art building anymore..
most RE games dont spend much time in one setting if you think about it..
RE1 speed through the mansion to the lab,
RE2 RPD station to lab again.
RE3 RPD station for not long at all,then clocktower then lab.
RE4 village followed by lab type of place.