The next place I used it was just after i placed the 3rd tablet into the observatory room so make sure you go back and get it before placing the 3rd tablet into the holder!
In RE-0, just after you save Rebecca from falling into the hole, there is a cut scene involving Birkin and Wesker. Wesker notes that he will be sending the S.T.A.R.S unit into the mansion as a test for the T-Virus. (would that indicate that maybe Wesker was involved in releasing the T-Virus upon...
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