At one time on this very forum I vehemently defended the Resident Evil films as being in their own universe and not needing to be a carbon copy of the game series.
I saw The Final Chapter when it came out in theaters and was utterly disappointed by it. First and foremost would be the fact that Paul Anderson concocted yet another origin story for the T Virus, totally disregarding the other origin story that he had written (with Ashford and his daughter in Resident Evil Apocalypse), amongst other things. I think that if nothing else, he had a duty to be true to the universe that he created and he failed to do that. Also, he proved once again that he doesn't research well. I'm referring of course to the presence of Progeria as a central story line to not just The Final Chapter, but as it turns out, much of the central story. I can't really say much else without spoiling anything, but it wasn't an accurate portrayal in the slightest and was very disappointing. For some reason, this bothered me (I don't know if it's just me being weird or what): Alice and company get stuck in the monitor room outside the Red Queen housing chamber and laser hallway with no hope and no weapons, but WAIT! That highly trained military unit that entered The Hive in the first movie, who were sitting in that very room with NO ammo magically didn't see the GIANT bag of guns and ammo that they apparently placed there before entering the laser hallway JUST SO that in The Final Chapter, Alice and company could have weapons at their disposal. Major shenanigans, I'm sorry. I just can't take this movie seriously.
I'm no pro by any means, but I have made amateur zombies films. I have written cohesive horror novels. There is no excuse for going against everything you've created so that your last project will appear to work, because all those people who faithfully followed YOUR universe apparently know that universe's rules better than you do.
*sigh* There really weren't any redeeming features for me in The Final Chapter. The writing was ****. The characters were not done justice (talking mainly about Wesker) and I spotted the ending miles away. I do not recommend it. It's one of those movies you shove off and pretend never happened in my opinion. :/